Windows Keyboard Shortcuts

Given below are some commonly used Windows keyboard shortcuts:

CTRL+C: Copy (to copy, highlight / select the object you wish to copy and then run this key combination)
CTRL+V: Paste (place the cursor where you wish to paste, and then type this key combination, to paste)
CTRL+X: Cut (“cutting” and “pasting” is nothing but “moving” an object to a different location.)
CTRL+Z: Undo
CTRL+B: Bold
CTRL+U: Underline
F1 : Help (for any application, including Windows)
ALT+F4: Quit current program/application
CTRL+ESC: Start menu
ALT+TAB: Switch between open programs
SHIFT+DELETE: Delete any item permanently
ALT+SPACE: Displays the main window’s System menu (from where you can restore, move, resize, minimize, maximize, or close the window)
F10:     Activates Menu Bar options
SHIFT+F10: same as right-clicking on an object
CTRL+SHIFT+ESC: Opens Windows Task Manager
SHIFT:     Press and hold down the SHIFT key while you insert a CD-ROM to bypass the automatic-run feature
Windows Logo + R:     Opens the Run Dialogue Box
Windows Logo + E:     Opens a new Windows Explorer window
Windows Logo + D:     Shows the Desktop (Minimizes all open windows)
Windows+Shift+M:     Restores all the minimized windows
Windows Logo + F:     Opens the Find Files and Folders dialogue box
Windows Logo + F1:   Opens the Windows Help and Support Center
Windows Logo Key:     Opens the Start Menu (Same as clicking on the Start Button)
Windows Logo + U:     Displays the Windows Utility Manager – Magnifier, Narrator, On-Screen Keyboard
Windows Logo + Pause / Break key:     Opens the System Properties window
Windows Logo + L:     Lock the computer (same as using CTRL+ALT+DELETE)

For a more detailed list, check out this Microsoft Knowledge-base article.